PRF vs. PRP: What’s the Difference in Regenerative Aesthetics?

In the ever-evolving world of regenerative aesthetics, two standout treatments are transforming the way we approach anti-aging and natural rejuvenation: PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin). While they may sound similar—and both harness the healing power of your own blood—there are key differences in how they’re processed, how they work, and the kinds of results they deliver.

Let’s break it down.

What is PRP?

Platelet-Rich Plasma (PRP) is a treatment that involves drawing a small amount of your blood, spinning it in a centrifuge to isolate the plasma and platelets, and re-injecting it into targeted areas of the skin or scalp. PRP is rich in growth factors that stimulate healing, collagen production, and tissue regeneration.

Benefits of PRP:

  • Improves skin texture and tone
  • Reduces fine lines and acne scars
  • Stimulates hair regrowth
  • Enhances healing post-microneedling or laser treatments

However, PRP has a shorter lifespan—it releases its growth factors over a few hours, meaning the regenerative benefits are more immediate but not as prolonged.

What is PRF?

Platelet-Rich Fibrin (PRF) is considered the next generation of PRP. It’s also made from your own blood—but the preparation is gentler, spun at a lower speed and without anticoagulants or additives. This allows more white blood cells, fibrin, and stem cells to remain in the solution, creating a natural matrix that gradually releases growth factors over 7 to 10 days instead of just hours.

Benefits of PRF:

  • 100% natural – no chemicals or additives
  • Slower, longer release of growth factors
  • Higher concentration of white blood cells and stem cells
  • Improves volume, firmness, and elasticity
  • Reduces dark circles, deep folds, and skin laxity
  • Encourages long-term collagen production

PRF is often preferred for more dramatic, longer-lasting results and is ideal for under-eye hollows, smile lines, and areas where you want both volume and rejuvenation.

What is Pure BioFill PRF?

One of the latest innovations in regenerative medicine is Pure BioFill PRF, a 100% autologous (from your own body) alternative to traditional dermal fillers. Created using your PRF and plasma proteins, it’s heated into a gel-like consistency that mimics the look and feel of a filler—without introducing any synthetic substances.

Pure BioFill PRF is ideal for:

  • Smoothing smile lines
  • Lifting under-eye hollows
  • Restoring volume to cheeks and temples
  • Softening facial folds
  • Promoting long-term collagen growth

It’s safe, natural, and incredibly effective for those looking for a regenerative option without traditional filler ingredients.

PRF vs. PRP – What’s the Real Difference?

FeaturePRPPRF
Centrifuge SpeedHigh speedLow speed
Additives UsedAnticoagulants addedNo additives (100% natural)
Growth Factor ReleaseQuick release (few hours)Slow release (7–10 days)
Cell ContentPlateletsPlatelets + WBCs + stem cells
Fibrin MatrixNot presentPresent (enhances volume + release)
Volume RestorationMildModerate to significant
LongevityShort to moderateLonger-lasting effects

So, Which One is Right for You?

  • Choose PRP if you’re new to regenerative treatments or want a quick refresh in skin tone, texture, or hair density.
  • Choose PRF if you want deeper, longer-lasting collagen stimulation, natural volume restoration, and a more dramatic anti-aging effect.
  • Choose Pure BioFill PRF if you’re looking for a natural, needle-injected alternative to dermal fillers with zero synthetic materials and regenerative benefits that build over time.

Now Offering: Pure BioFill PRF Launch Special!

🎉 Buy Two Treatments, Get Your Third Free
💰 Just $1,998 total – You save $999

Experience the future of regenerative aesthetics at Aluma Wellness with our newest launch — Pure BioFill PRF by RejuvaPen. This special is only available for a limited time. Don’t miss your chance to glow naturally from the inside out.

📲 Call or Text us at 407-910-1028 to schedule your consultation and start your skin’s transformation — the natural way.


Call Now Button